Live fermented milk bacteria lyofirizirovanny Linex Forte N14

Composition
Linex Forte contains Lactobacillus acidophilus and Bifidobacterium animalis subsp. As active ingredients. As an additional substance, the preparation contains: Beneo Synergy 1, MCC, anhydrous glucose, potato starch, magnesium stearate.
Pharmacological effect
The drug that regulates the balance of intestinal microflora. One capsule of the drug Linex Forte contains 2 × 109 colony-forming units of live lyophilized lactic acid bacteria: Lactobacillus acidophilus (LA-5) and Bifidobacterium animalis subsp. lactis (BB-12). Live lactic acid bacteria are a normal component of the natural intestinal microflora. Lactic acid bacteria perform a protective function, synthesizing substances with antibacterial activity, produce enzymes, under the influence of which hydrolysis of cellulose, proteins, fats, starch and bile acid deconjugation occurs, and also participate in the synthesis of vitamins B, C, K, amino acids, organic acids. The lactic acid bacteria LA-5 and BB-12 inhibit the growth of pathogenic bacteria by: shifting the intestinal pH to the acid side (the result of the ability of LA-5 to synthesize lactic acid and BB-12 to synthesize acetic and succinic acids in addition to lactic acid), the production of metabolites that have a toxic effect on pathogenic bacteria (formation of H2O2), formation of antimicrobial substances, bacteriocins (LA-5 secretes acidocyan, a broad-spectrum bacteriocin, which inhibits the growth of bacteria and fungi), competitive With pathogenic bacteria for nutrients, interactions with adhesion receptors, thus preventing the colonization of other potentially pathogenic microorganisms.
Pharmacokinetics
Lactic acid bacteria, such as LA-5 and BB-12, act directly in the gastrointestinal tract; when taken orally, the drug is not subjected to systemic absorption. Standard pharmacokinetic studies are therefore not applicable. The resistance of LA-5 and BB-12 to the effects of gastric juice and bile allows the strains to maintain their viability in large quantities when passing through the stomach and duodenum. Both strains are attached to the intestinal mucosa. Like other microorganisms, gradually excreted from the gastrointestinal tract with feces.
Indications
Treatment and prevention of intestinal dysbiosis
Contraindications
Hereditary fructose intolerance, sucrase-isomaltase deficiency or glucose / galactose malabsorption syndrome. hypersensitivity to the components of the drug. With caution, you should use the drug for diabetes mellitus (it consists of simple sugars), a failure of the immune system (for example, HIV infection).
Precautionary measures
The drug should be used with caution in case of diabetes mellitus (it consists of simple sugars), immune system deficiencies (for example, HIV infection).
Use during pregnancy and lactation
Due to the lack of data on the use of the drug in pregnant women, it is not recommended to take Linex Forte during pregnancy and lactation (breastfeeding) without prior consultation with a doctor. In the appointment of the drug for the treatment of acute diarrhea during pregnancy and lactation, it is necessary to monitor the doctor.
Dosage and administration
The drug is taken inside, preferably during or after a meal. Capsules should be taken with a small amount of liquid. When prescribing the drug Linex Forte to children and patients who cannot swallow the capsule entirely, it should be opened, pour the contents into a spoon and mix with a small amount of liquid. Adults and adolescents over 12 years old are prescribed 1 caps. 1-3 times / day Children aged 2 to 12 years – 1 caps. 1-2 times / day. Newborns and children under the age of 2 years – 1 caps. 1 time / day Diarrhea in children under 6 years old must be treated under the supervision of a physician. The duration of treatment depends on the cause of the development of dysbiosis and the individual characteristics of the organism. The drug Linex Forte can be taken until the symptoms of dysbacteriosis disappear.
Side effects
The drug is well tolerated. No adverse effects have been reported, but hypersensitivity reactions may occur.
Overdose
Data on the symptoms of an overdose of the drug Linex Forte is not.
Interaction with other drugs
No undesirable interaction of the drug Linex Forte with other drugs was noted. With the simultaneous use of antibiotics, the recommended interval between taking the drug (antibiotic) and capsules Linex Forte should be 3 hours.

Packing quantity: 14 pcs
Expiration date: 24 months
Maximum allowable storage temperature: + 5 ° C + 25 ° C
Release form: Capsules
Country of origin: Slovenia
Active ingredient: Lactobacillus acidophilic (Lactobacillus acidophilus)
Scope of application: Gastroenterology
Release form: Capsules
Country of origin: Slovenia