Carsil® Max belongs to the group of hepatoprotective drugs. Contains dry extract of milk thistle fruit (silymarin equivalent), which is a mixture of 4 isomers of flavonolignans: silibinin, iso-silibinin, silidianin and silicristin.
The mechanism of action of the drug is still not well understood. It has been established that the hepatoprotective effect of silymarin is due to competitive interaction with toxins on the corresponding receptors in the membrane of hepatocytes, thus exhibiting a membrane stabilizing effect.
The drug has metabolic and cell-regulatory effects, regulating the permeability of the cell membrane, inhibiting the 5-lipoxygenase pathway, in particular leukotriene B4 (LTB4), as well as binding to free oxygen radicals.
Stimulates the synthesis of proteins (structural and functional) and phospholipids in the affected hepatocytes, accelerating the regenerative processes.
The action of flavonoids, to which silymarin belongs, is also due to their antioxidant and microcirculation-improving effects.
Clinically, these effects are expressed in the improvement of subjective and objective symptoms and in the normalization of indicators of the functional state of the liver (transaminases, gammaglobulin, bilirubin). This leads to an improvement in the general condition, a decrease in complaints related to digestion, and in patients with reduced absorption of food due to liver disease, it leads to an increase in appetite and an increase in body weight.
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