Pharmacodynamics
Choleretic (cholekinetic and choleretic) agent, reduces the processes of putrefaction and fermentation in the intestines. Strengthens the secretory function of liver cells, reflexively increases the secretory and motor activity of the organs of the gastrointestinal tract. Strengthens the formation of bile and bile acids. The action of bile is due to the reflex effect on the secretory function of the liver parenchyma. Bile also enhances the secretory and motor functions of the gastrointestinal tract. The substances contained in garlic enhance the secretory and motor function of the gastrointestinal tract, stimulate the secretion of bile. Nettle leaves have choleretic and anti-inflammatory properties. Activated carbon is an adsorbent that binds toxic substances in the gastrointestinal tract.
Pharmacokinetics
The drug is well absorbed in the gastrointestinal tract. Cholic and chenodeoxycholic acids contained in the preparation undergo 7-alpha-dehydroxylation in the intestine. Chenodeoxycholic acid, in addition, undergoes metabolism in the liver: it conjugates with amino acids, is secreted into bile, from where it is again secreted into the intestine, then partially reabsorbed; the rest is excreted through the intestines.
Indications
As part of complex therapy: chronic reactive hepatitis, cholangitis, acalculous (non-calculous) cholecystitis, hypokinetic biliary dyskinesia, atonic constipation, postcholecystectomy syndrome.
Method of administration and dosage
Inside, after eating.
Adults – 1-2 tablets 3-4 times a day. Children over 12 years old – 1 tablet 3 times a day. The course of treatment is 3-4 weeks.
In case of exacerbation of the disease, 1 tablet 2-3 times a day for 1-2 months.
Repeated courses of treatment are carried out at intervals of 3 months after consulting a doctor.
Before using the drug in children, you should consult a doctor.
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