NATURAL ACTIVATED Carbon Charcoal 250 mg х 200 tab ENTEROSORBENT AVEXIMA PREMIUM

Special conditions
In the treatment of intoxications, it is necessary to create an excess of activated carbon in the stomach (before washing it) and in the intestine (after washing the stomach). A decrease in the concentration of activated carbon in the medium promotes the desorption of the bound substance and its absorption (to prevent the resorption of the released substance, repeated gastric lavage and the appointment of activated carbon are recommended). The presence of food masses in the gastrointestinal tract requires administration in high doses, since the contents of the gastrointestinal tract are sorbed by activated carbon and its activity decreases. If the poisoning is caused by substances involved in enterohepatic circulation (cardiac glycosides, indomethacin, morphine and other opiates), activated charcoal must be used for several days. When using the drug for more than 10-14 days, prophylactic administration of vitamins and calcium preparations is necessary. It is recommended to store it in a dry place away from substances that emit gases or vapors into the atmosphere. Storage in air (especially humid) reduces sorption capacity.
Influence on the ability to drive vehicles, mechanisms
The use of the drug does not affect the ability to perform potentially hazardous activities requiring increased concentration of attention and speed of psychomotor reactions (driving vehicles, working with moving mechanisms, the work of a dispatcher and an operator).

Drug interactions
Activated carbon reduces the effectiveness of drugs taken simultaneously, reduces the effectiveness of drugs acting on the mucous membrane of the gastrointestinal tract (including ipecac and thermopsis).

Dosage form
Tablets are black, flat-cylindrical with a chamfer or with a chamfer and a score, slightly rough.

Composition
one tablet contains:
Active ingredient: – activated carbon – 250 mg.
Excipient: potato starch – 47 mg.

Pharmacodynamics
It has an enterosorbent, detoxifying and antidiarrheal effect. It belongs to the group of polyvalent physicochemical antidotes, has a high surface activity. Adsorbs poisons and toxins from the gastrointestinal tract before their absorption, including alkaloids, glycosides, barbiturates and other hypnotics and narcotics, salts of heavy metals, toxins of bacterial, plant, animal origin, derivatives of phenol, hydrocyanic acid, sulfonamides, gases. The drug also adsorbs an excess of some metabolic products – bilirubin, urea, cholesterol, as well as endogenous metabolites responsible for the development of endogenous toxicosis. Weakly adsorb acids and alkalis (including iron salts, cyanides, malathion, methanol, ethylene glycol). It is active as a sorbent in hemoperfusion. Does not irritate the mucous membrane of the gastrointestinal tract.

Pharmokinetics
Not absorbed, not degraded, excreted completely through the gastrointestinal tract within 24 hours.

Indications
It is used as a detoxifying agent for exogenous and endogenous toxicosis of various nature. In the complex treatment of food toxicoinfection, salmonellosis, dysentery. In case of poisoning with drugs (including psychotropic, hypnotic, narcotic drugs), alkaloids, heavy metal salts and other poisons. With diseases of the gastrointestinal tract, accompanied by dyspepsia, flatulence. For food and drug allergies. With hyperbilirubinemia (viral hepatitis and other jaundice). With hyperazotemia (renal failure). To reduce gas formation in the intestine before ultrasound and X-ray examinations.

Contraindications
Exacerbation of gastric ulcer and duodenal ulcer, ulcerative colitis, bleeding from the gastrointestinal tract, intestinal atony, individual drug intolerance, simultaneous administration of antitoxic drugs, the effect of which develops after absorption (methionine, etc.).
Application during pregnancy and during breastfeeding.
It is possible to use the drug during pregnancy and during breastfeeding, if the expected benefit to the mother outweighs the potential risk to the fetus and child. It is necessary to consult a doctor.

Overdose
To date, no cases of overdose have been registered.

Side effects
Dyspepsia, constipation or diarrhea, dark staining of feces. With prolonged use (more than 14 days), it is possible to reduce the absorption of vitamins, calcium and other nutrients from the gastrointestinal tract.

Application methods
Administered orally in tablets or, after preliminary grinding, in the form of an aqueous suspension, one hour before meals and taking other medicines. The required amount of the drug is diluted in ½ glass of water.
Dosage regimen: adults are prescribed an average of 1.0-2.0 g (4-8 tablets) 3-4 times a day. The maximum single dose for adults is up to 8.0 g (16 tablets). For children, the drug is prescribed on average at the rate of 0.05 g / kg 3 times a day, depending on body weight. The maximum single dose is up to 0.2 g / kg of body weight. The course of treatment for acute diseases is 3-5 days, for allergies and chronic diseases – up to 14 days. A second course in 2 weeks on the recommendation of a doctor.
In acute poisoning, treatment begins with gastric lavage, using a suspension of activated carbon, then give 20-30 g of the drug inside. When flatulence is prescribed orally 1.0-2.0 g (4-8 tablets) 3-4 times a day. The course of treatment is 3-7 days.

Specifications
Active ingredients: activated carbon
Country of origin Russia
Manufacturer Avexim Sibir LLC
Release form Tablets 250 mg – 50 pieces per pack.
Keep out of reach of children